Paul Pogba, however, remains doubtful after having only participated during the final stages of the training session held on Monday morning.
Strikers Zlatan Ibrahimovic and Anthony Martial did take part, but Marcos Rojo, Phil Jones, Daley Blind and Ander Herrera were missing.
Manchester United captain Michael Carrick has confirmed he is to call it quits with professional football at the end of the season.
The Round of 16 tie is evenly poised after the first leg in Spain, where the two sides failed to find the back of the net. There were, however, wins against both Malaga and Athletic Bilbao in between that sandiwch of defeats.
"I think we're not one of the best teams in the competition", said Mourinho.
"It is a big opportunity for us, " said the Italian, who will be without former Manchester City wide man Jesus Navas through injury.
Marcus Rashford rose to the occasion in his first Premier League start since Boxing Day, scoring twice against Liverpool.
At Old Trafford, Jose Mourinho's side should have the encouragement to attack from the off, but they still need to be wary of conceding an away goal, which could be detrimental, as they would then have to score at least twice, to stay in the competition.
At the Movies - "A Wrinkle in Time"
There's likely another version of this movie that's less odd, that's more straightforward, more predictable, and more lifeless. The relationship between brother and sister in this film is one that most parents dream of, and is actually believable.
Manchester United boss Jose Mourinho says Alexis Sanchez is still adapting to life at the club and says the winter market makes it hard for players to hit the ground running.
He was upset with a player and the same happened to me against Crystal Palace, where I was upset with my player and therefore they [the officials] understood that too. Nemanja Matic struck home a gorgeous half-volley in added time for a remarkably good comeback.
"We are reaching an important time in the season, the key moment, and the team needs total concentration on the pitch to achieve our goals". "I would sign right now to draw 1-1 at Manchester".
For 24-year-old Pogba, he was not named in Jose Mourinho's squad which pulled off a 2-1 victory over Liverpool at the weekend after sustaining a thigh injury in training.
Meanwhile, Sevilla have been more inconsistent in recent weeks.
He also helped United win the UEFA Champions League (2008), FIFA Club World Cup (2008) and the UEFA Europa League (2017). "He put in a great performance in the first leg and it would be great to put in a repeat for us". But a second-half comeback was typical more of the teams of old.
"I am anxious. United are a strong, physical side and I am expecting the same as in the first leg".
"To keep going and try to get through to the quarterfinal would be great for us".