UnitedHealth rose 1.9 percent after the largest USA health insurer reported results that beat estimates and raised its 2018 earnings outlook.
Hopes of strong quarterly earnings, supported by steep cut in corporate taxes, and solid global economic growth have bolstered Wall Street's optimism in the start to 2018.
In late afternoon trading, the Dow Jones Industrial Average had lost momentum and was down 0.11 per cent at 25,775.87.
The pan-European Stoxx 600 index ended flat, while euro zone stocks added 0.3 per cent as the euro gave up some of its strength against the dollar.
Losses by industrial and technology companies helped pull US stocks mostly lower in late-afternoon trading Tuesday, placing the market on course for modest losses.
KEEPING SCORE: The Standard & Poor's 500 index fell 8 points, or 0.3 percent, to 2,777 as of 2:31 p.m.
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General Electric fell about 4 per cent after raising the prospect of breaking itself up and announced more than $11 billion in charges from its long-term care insurance portfolio and new USA tax laws. The institutional investor owned 2,273 shares of the exchange traded fund's stock after selling 409 shares during the period.
Apple and Microsoft each rose 1 per cent in early trading Tuesday.
Crude oil prices were were about 1 percent lower and under $64 per barrel. Range Resources slid 71 cents, or 4 percent, to $16.87.
Volume on USA exchanges was 8.30 billion shares, compared to the 6.48 billion average over the last 20 trading days.
Amazon rose more than 2 percent, extending gains from last week when data showed US holiday spending surged to 12-year high, prompting price target hikes. The yield on the 10-year Treasury held steady at 2.55 percent. South Korea's top financial policymaker said Tuesday that banning trading in digital currencies was an option, adding such a move still needed to be reviewed by government ministries.
Frankfurt's DAX rose 0.35 per cent to 13,246.33. London's FTSE 100 shed 0.2 percent.
Canada police search for atacker who cut 11-year-old girl's hijab
A short time later, he returned to assault her again and ended up cutting 11 inches (30 centimeters) from her hijab, she said. Toronto police are searching for a man who allegedly cut a young girl's hijab with a pair of scissors on her way to school.