Foreign Minister Maria Fernanda Espinosa said Tuesday that Ecuador was in close contact with Britain and might seek mediation to solve a situation she described as "unsustainable".
Assange, 46, has been living in the London embassy of the south American country for five-and-a-half years after being granted political asylum as he fought sex-related claims in Sweden.
Assange faces both criminal and congressional investigations in the United States.
"The government of Ecuador recently requested diplomatic status for Mr Assange here in the United Kingdom", the spokesman said on Thursday.
Wikileaks leader Julian Assange is on the brink of losing his sanctuary at the Ecuadorian embassy.
Wikileaks founder Julian Assange addresses the media from the balcony of Ecuador's London embassy.
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News of his naturalization comes a day after he it was revealed he had been given an Ecuadorian passport.
At the beginning of January, it was reported that us lawyers who worked on Donald J. Trump's presidential campaign were working to remove the threat of arrest placed on Mr. Assange by federal authorities.
The Australian-born Assange posted a photograph of himself wearing a yellow Ecuadorean national soccer team jersey on Instagram Wednesday and his name now appears in the Andean country's national registry.
His radical anti-secrecy agenda has polarised opinion between those who hail him as a hero, and critics who say WikiLeaks has put lives in danger by releasing confidential government documents. The entry shows that the country issued the passport on December 21st, nearly three weeks ago - and more than two weeks before Espinosa asked for assistance in getting Assange out of their embassy. "No solution can be reached without global cooperation and without cooperation from the United Kingdom, which in addition has shown interest in finding a solution".
U.S. Attorney General Jeff Sessions, responding to a reporter's question in April about whether arresting Assange was a priority, said it was.
The Swedish prosecutors halted the case against Assange in September 2017.
This sparks speculation that Assange is about to end his self-imposed exile.