Jimmy Garoppolo and the 49ers' offense did not immediately continue the ride of momentum from his first week as a starter. Lamm became the fifth Texans player in two weeks to depart a game with a concussion.
Garoppolo, who arrived in Santa Clara on October 31 after a trade with the New England Patriots, has the most yards passing for any 49ers quarterback making his first two starts since the National Football League merger in 1970. Garoppolo engineered a game-winning drive in the fourth quarter last week at Chicago.
The game was tied when he found Garrett Celek on a 6-yard touchdown pass with about two minutes left in the third quarter to make it 23-16.
Their third scoring drive was particularly impressive, with the 49ers covering 62 yards in six plays and 54 seconds and Gould nailing a 35-yard field goal as the first half expired.
That was the first of five consecutive possessions that ended with a score for the 49ers. Completions of 29 and 31 yards to Kyle Juszczyk set up San Francisco's first touchdown. Houston opened the scoring on Ka'imi Fairbairn's 55-yard field goal.
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Savage had been benched earlier in the season in favor of Watson and has been 1-5 in his starts during the 2017 season. Hopkins caught 11 passes for 149 yards and two touchdowns. Savage suffered a concussion during the game. Johnson was observed spiking his helmet on the sideline after getting beaten for the touchdown.
Houston quarterback Tom Savage was cleared to re-enter Sunday's game against the San Francisco 49ers for one series after sustaining a concussion, raising questions about the NFL's procedure for evaluating such injuries during games.
T.J. Yates replaced Savage late in the first half and led the Texans on touchdown drives on his first two drives.
Tom Savage is taken to the locker room after scary scene in Houston Sunday.