"They say you play the John Peel Stage twice in your career - once on the way up, and once on the way down", said frontman Brandon Flowers.
The singer repeatedly recited Mrs May's "strong and stable" election slogan during the band's headline set on the Pyramid Stage.
With an arena tour done and dusted, a stadium tour booked for next year and Glastonbury the latest addition to the Sheeran win column, there will soon be no worlds left for him to conquer.
Understandably, no one ever thinks of Ed Sheeran as someone who deals in mind-blowing sonic overload, but on the live versions of Bloodstream and You Need Me, the constant overdubbing of guitar eventually results in a genuinely thrilling racket, visceral and propulsive.
The band took to the iconic Pyramid stage at Worthy Farm in Somerset to join Ed in a rendition of Nancy Mulligan in front of thousands of fans.
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So too would chairman Khaldoon Al Mubarak, who declared in May there had " never been a doubt " Aguero could leave Manchester. Over the last few months, the Chile global has been linked to Chelsea, Paris Saint-Germain and Bayern Munich.
Other top acts on the bill during the festival included included Katy Perry, Liam Gallagher, Kaiser Chiefs, Emeli Sande, Status Quo, Goldfrapp, The Pretenders, The Jacksons, Dizzee Rascal, Alison Moyet and Kiefer Sutherland.
Headlining the festival for the third time, the gig marked 20 years since the band's legendary rain-sodden 1997 performance, often called one of the best shows in Glastonbury's 47-year history. "It was unreal, man", recalled a clearly-moved Rodgers, who said he'd been packing and shipping clothing as part of the volunteer effort.
A litter picking crew of up to 800 has begun clearing the huge area of rubbish, with tractors carrying magnetic strips travelling across the fields.
The mission to convert it back into a functioning dairy farm could take up to six weeks. The footballer arrived prior to his wife, with their son Brooklyn, to support a project developed by Glastonbury organiser Michael Eavis, in the nearby village of Pilton.
In fact, the "Everlong" singer has beaten Adele's swearing record at last year's Glastonbury. "Half a century. It's an incredible feat, actually".
"Until then it's an uphill struggle convincing the rest of the music world that Cornwall is a serious touring destination, but we're working on it!"